Scaling of a reverse osmosis membrane may occur when sparingly soluble salts are concentrated within the element beyond their solubility limit. In a RO system the most common sparingly soluble salts encountered are CaSO4, CaCO3 and silica. Other salts (especially in sea water) creating a potential scaling problem are CaF2, BaSO4 and SrSO4. Anti-scalants (scale inhibitors) are used to preventing the fouling of RO membrane elements due to the formation of scale. The anti-scalants inhibit the nucleation step of salts in the concentrate of RO system and so delay crystal and precipitate occurrence.
| 
             Foulants Antiscalants 
             | 
            Inorganic scales | Silica scale | Colloid foulant | Organic foulant | Biologic foulant | 
| CaCO3, Ca/Ba/Sr SO4, Metal oxide | Colloidal silica Reactive silica  | 
            Colloidal silt Particulate  | 
            Humic acid Lignin, oil  | 
            Bacteria, mold, fungi, yeasts | |
| 
             MAS 200 
             | 
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| 
             MAS 400 
             | 
            ● | ||||
| 
             MAS 500 
             | 
            ● | ● | ● | ||
| 
             MAS 800 
             | 
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